Book Description

James A. Shapiro’s Evolution: A View from the 21st Century proposes an important new paradigm for understanding biological evolution. Shapiro demonstrates why traditional views of evolution are inadequate to explain the latest evidence, and presents a compelling alternative. His information- and systems-based approach integrates advances in symbiogenesis, epigenetics, and mobile genetic elements, and points toward an emerging synthesis of physical, information, and biological sciences.

From the Back Cover
“Shapiro has written a stimulating, innovative manuscript that surely Darwin would have liked.”
—Sidney Altman, Yale University; Nobel Laureate in Chemistry, 1989

“Based on a long and highly competent personal experience in science and his novel insights into biological functions, the author has reached views of biological evolution that can reveal to a wide, interested readership how the living world co-evolves with the environment through its intrinsic powers.”
—Werner Arber, Professor Emeritus, University of Basel, Switzerland; Nobel Laureate in Physiology/Medicine, 1978

“Professor Shapiro’s offering is the best book on basic modern biology I have ever seen. As far as I can tell, the book is a game changer.”
—Carl Woese, University of Illinois; discoverer of Archaea, the third realm of life; National Medal of Science 2000 Download Now »

Book Description

Leading medical genetics scholar Moyra Smith reviews current prospects and progress in medical genetics and genomics, arising from the growth of gene mapping and Human Genome sequencing. She addresses recent investigations into human origins, migrations, and diversity; psychiatric diseases; Alzheimer’s, Parkinsonism, and ALS; protein misfolding; gene-environment interactions; mRNA; epigenetics, and much more

From the Back Cover
An Up-to-Date Assessment of Recent Advances in Human Genetics, Human Variation,and Gene-Related Disease

In Investigating the Human Genome, leading medical genetics scholar Moyra Smith reviews current and recent work in genetics and genomics to assess progress in understanding human variation and the pathogenesis of common and rare diseases in which genetics plays a role.

Smith provides an exceptional overview of the most important biomedical progress arising from the greatly increased genetic information base generated by gene mapping and the sequencing of the complete Human Genome. She addresses diverse topics associated with human genetics and genomics, ranging from psychiatric and late-onset illness to early human history.

Coverage includes

• Genetic research on human origins, migrations, and population diversity
• Genome architecture and sequence variation in health and disease Download Now »

Book Description

You’ll learn how to handle each aspect of the flexible Scrivener manuscript-generation process:
Set up: Add reference materials to your project for easy access – videos, audio files, PDFs, Web resources, and more. And, if you’ve already written bits of text, you can import those items too, including OPML outline files (such as from OmniOutliner Pro). Beyond importing from the Finder, you can use Mac OS X Services or Scrivener’s handy Scratch Pad panel. Or, you can use the Import and Split feature to import a long document into multiple chapters or segments in Scrivener.

Organize: Use the Outliner, Corkboard, Collections, and Binder to mix and match your content into the perfect final arrangement. For example, you can:

• Ignore the concept of a traditional file and break your manuscript into sections based on character, theme, topic, scene, or whatever you like.
• Organize your manuscript linearly in the Outliner.
• Use search Collections to search for a character, location, or phrase and see just those texts.
• Organize ideas by dragging and pinning index cards on the Corkboard.

Write: Use Full Screen mode to hide distractions so you can wordsmith in peace; set up Typewriter Scrolling to keep your writing focus at the center of the screen, not the bottom; and view more than one part of your project at once, so you can write in one section while referring to another. Also, use Scrivenings view to write one thread of a story all at once in a single view, even if it is broken up in multiple scenes or chapters in the final manuscript. Download Now »

Book Description

TIBCO’s product suite comprises a diverse range of components. Each component is specialized for a particular functionality, ranging from basic messaging through services, service orchestration, the management of complex business processes, managing master data across multiple systems, and the interpretation ofmassive streams of events (complex event processing).

The architecture series from TIBCO® Press comprises a coordinated set of books for software architects and developers, showing how to combine TIBCO components to design and build real-world solutions.

TIBCO® Architecture Fundamentals is the core book for understanding and using the TIBCO product suite. It focuses on the TIBCO ActiveMatrix® product suite and a handful of the other most commonly used components, including the TIBCO Enterprise Message Service^TM and TIBCO BusinessEvents^TM. The book provides a sound basis for applying TIBCO products to solve the most common integration and SOA challenges faced by architects and developers. In addition, it lays the foundation for the more advanced books to be added to the architecture series.

Designed to make the material as accessible as possible, the book starts with concrete problems architects and developers face every day, showing how to solve these problems with combinations of TIBCO (and selected third-party) products. In the context of specific design scenarios, it also discusses key concepts and decision trade-offs. To accomplish its practical aims, the book Download Now »

Book Description

Step-by-Step, Full-Color Graphics!

Take advantage of your computer’s features and tools right away–the QuickSteps way. Color photos and screenshots with clear instructions make it easy to accomplish everything you want to do. Follow along and quickly learn how to navigate the Windows operating system; get online; use core programs such as Word, Excel, and Quicken; and secure your computer. Fun activities, such as genealogy, photo editing and management, social networking, and online dating are covered, plus you’ll get tips for enjoying music, ebooks, and videos. Written by seniors for seniors, this practical, fast-paced guide helps you get the most out of your computer.

Use these handy guideposts:

• Shortcuts for accomplishing common tasks
• Personal insights from other seniors
• Need-to-know facts in concise narrative
• Helpful reminders or alternative ways of doing things
• Bonus information related to the topic being covered
• Errors and pitfalls to avoid Download Now »

Book Description

Discover BIM: A better way to build better buildings

Building Information Modeling (BIM) offers a novel approach to design, construction, and facility management in which a digital representation of the building process is used to facilitate the exchange and interoperability of information in digital format. BIM is beginning to change the way buildings look, the way they function, and the ways in which they are designed and built.

The BIM Handbook, Second Edition provides an in-depth understanding of BIM technologies, the business and organizational issues associated with its implementation, and the profound advantages that effective use of BIM can provide to all members of a project team. Updates to this edition include:

• Completely updated material covering the current practice and technology in this fast-moving field
• Expanded coverage of lean construction and its use of BIM, with special focus on Integrated Project Delivery throughout the book
• New insight on the ways BIM facilitates sustainable building
• New information on interoperability schemas and collaboration tools
• Six new case studies Download Now »